The phage T4 DNA ligase in vivo improves the survival-coupled bacterial mutagenesis

BACKGROUND: Microbial mutagenesis is an important avenue to acquire microbial strains with desirable traits for industry application. However, mutagens either chemical or physical used often leads narrow library pool due to high lethal rate. The T4 DNA ligase is one of the most widely utilized enzym...

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Detalles Bibliográficos
Publicado en:Microb Cell Fact
Main Authors: Wang, Junshu, Liu, Fapeng, Su, Tianyuan, Chang, Yizhao, Guo, Qi, Wang, Qian, Liang, Quanfeng, Qi, Qingsheng
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567493/
https://ncbi.nlm.nih.gov/pubmed/31196093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-019-1160-7
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