Therapeutic Effects of rAAV-Mediated Concomittant Gene Transfer and Overexpression of TGF-β and IGF-I on the Chondrogenesis of Human Bone-Marrow-Derived Mesenchymal Stem Cells

Application of chondroreparative gene vectors in cartilage defects is a powerful approach to directly stimulate the regenerative activities of bone-marrow-derived mesenchymal stem cells (MSCs) that repopulate such lesions. Here, we investigated the ability of combined recombinant adeno-associated vi...

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Udgivet i:Int J Mol Sci
Main Authors: Morscheid, Stephanie, Rey-Rico, Ana, Schmitt, Gertrud, Madry, Henning, Cucchiarini, Magali, Venkatesan, Jagadeesh Kumar
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567173/
https://ncbi.nlm.nih.gov/pubmed/31137788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20102591
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