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Dysregulation of Neuronal Genes by Fetal-Neonatal Iron Deficiency Anemia Is Associated with Altered DNA Methylation in the Rat Hippocampus

Early-life iron deficiency results in long-term abnormalities in cognitive function and affective behavior in adulthood. In preclinical models, these effects have been associated with long-term dysregulation of key neuronal genes. While limited evidence suggests histone methylation as an epigenetic...

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Detalhes bibliográficos
Publicado no:Nutrients
Main Authors: Lien, Yu-Chin, Condon, David E, Georgieff, Michael K, Simmons, Rebecca A, Tran, Phu V
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566599/
https://ncbi.nlm.nih.gov/pubmed/31137889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu11051191
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