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Fetal iron deficiency induces chromatin remodeling at the Bdnf locus in adult rat hippocampus

Fetal and subsequent early postnatal iron deficiency causes persistent impairments in cognitive and affective behaviors despite prompt postnatal iron repletion. The long-term cognitive impacts are accompanied by persistent downregulation of brain-derived neurotrophic factor (BDNF), a factor critical...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Tran, Phu V., Kennedy, Bruce C., Lien, Yu-Chin, Simmons, Rebecca A., Georgieff, Michael K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329464/
https://ncbi.nlm.nih.gov/pubmed/25519736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00429.2014
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