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Fetal iron deficiency induces chromatin remodeling at the Bdnf locus in adult rat hippocampus

Fetal and subsequent early postnatal iron deficiency causes persistent impairments in cognitive and affective behaviors despite prompt postnatal iron repletion. The long-term cognitive impacts are accompanied by persistent downregulation of brain-derived neurotrophic factor (BDNF), a factor critical...

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Pubblicato in:Am J Physiol Regul Integr Comp Physiol
Autori principali: Tran, Phu V., Kennedy, Bruce C., Lien, Yu-Chin, Simmons, Rebecca A., Georgieff, Michael K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329464/
https://ncbi.nlm.nih.gov/pubmed/25519736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00429.2014
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