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Engineering of Nanobodies Recognizing the Human Chemokine Receptor CCR7

The chemokine receptor CCR7 plays a pivotal role in health and disease. In particular, CCR7 controls homing of antigen-bearing dendritic cells and T cells to lymph nodes, where adaptive immune responses are initiated. However, CCR7 also guides T cells to inflamed synovium and thereby contributes to...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Jakobs, Barbara D., Spannagel, Lisa, Purvanov, Vladimir, Uetz-von Allmen, Edith, Matti, Christoph, Legler, Daniel F.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566259/
https://ncbi.nlm.nih.gov/pubmed/31137829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20102597
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