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Widely applicable background depletion step enables transaminase evolution through solid-phase screening

Directed evolution of transaminases is a widespread technique in the development of highly sought-after biocatalysts for industrial applications. This process, however, is challenged by the limited availability of effective high-throughput protocols to evaluate mutant libraries. Here we report a rap...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Chem Sci
Main Authors: Planchestainer, Matteo, Hegarty, Eimear, Heckmann, Christian M., Gourlay, Louise J., Paradisi, Francesca
Format: Artigo
Jezik:Inglês
Izdano: Royal Society of Chemistry 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566068/
https://ncbi.nlm.nih.gov/pubmed/31360401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc05712e
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