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Fluorofenidone affects hepatic stellate cell activation in hepatic fibrosis by targeting the TGF-β1/Smad and MAPK signaling pathways

The aim of the present research was to study the therapeutic impacts of fluorofenidone (AKF-PD) on pig serum (PS)-induced liver fibrosis in rats and the complex molecular mechanisms of its effects on hepatic stellate cells (HSCs). Wistar rats were randomly divided into normal control, PS and PS/AKF-...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Peng, Yu, Li, Li, Zhang, Xin, Xie, Mingyan, Yang, Congying, Tu, Sha, Shen, Hong, Hu, Gaoyun, Tao, Lijian, Yang, Huixiang
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566051/
https://ncbi.nlm.nih.gov/pubmed/31258636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7548
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