The purinergic receptor antagonist oxidized adenosine triphosphate suppresses immune-mediated corneal allograft rejection

Adenosine triphosphate (ATP) is released into the extracellular environment during transplantation, and acts via purinergic receptors to amplify the alloimmune response. Here, using a well-established murine model of allogeneic corneal transplantation, we investigated the immunomodulatory mechanisms...

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Publicado en:Sci Rep
Autores principales: Foulsham, William, Mittal, Sharad K., Nakao, Takeshi, Coco, Giulia, Taketani, Yukako, Chauhan, Sunil K., Dana, Reza
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565802/
https://ncbi.nlm.nih.gov/pubmed/31197223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44973-y
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