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The prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivo
Prion-like domains (PLDs), defined by their low sequence complexity and intrinsic disorder, are present in hundreds of human proteins. Although gain-of-function mutations in the PLDs of neuronal RNA-binding proteins have been linked to neurodegenerative disease progression, the physiological role of...
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| Publicat a: | Nat Commun |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6565635/ https://ncbi.nlm.nih.gov/pubmed/31197139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10554-w |
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