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Inhibition of Karyopherin beta 1 suppresses prostate cancer growth

Prostate cancer (PCa) initiation and progression requires activation of numerous oncogenic signaling pathways. Nuclear-cytoplasmic transport of oncogenic factors is mediated by Karyopherin proteins during cell transformation. However, the role of nuclear transporter proteins in PCa progression has n...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Yang, Jian, Gsuo, Yuqi, Lu, Cuijie, Zhang, Ruohan, Wang, Yaoyu, Luo, Liang, Zhang, Yanli, Chu, Catherine H, Wang, Katherine J, Obbad, Sabrine, Yan, Wenbo, Li, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565446/
https://ncbi.nlm.nih.gov/pubmed/30742095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0745-2
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