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Ligand Modulates Cross-Coupling between Riboswitch Folding and Transcriptional Pausing

Numerous classes of riboswitches have been found to regulate bacterial gene expression in response to physiological cues, offering new paths to anti-bacterial drugs. As common studies of isolated riboswitches lack the functional context of the transcription machinery, we here combine single-molecule...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell
Prif Awduron: Widom, Julia R., Nedialkov, Yuri A., Rai, Victoria, Hayes, Ryan L., Brooks, Charles L., Artsimovitch, Irina, Walter, Nils G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565381/
https://ncbi.nlm.nih.gov/pubmed/30388413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.08.046
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