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Functional paralysis of human natural killer cells by alphaherpesviruses

Natural killer (NK) cells are implicated as important anti-viral immune effectors in varicella zoster virus (VZV) infection. VZV can productively infect human NK cells, yet it is unknown how, or if, VZV can directly affect NK cell function. Here we demonstrate that VZV potently impairs the ability o...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Campbell, Tessa Mollie, McSharry, Brian Patrick, Steain, Megan, Russell, Tiffany Ann, Tscharke, David Carl, Kennedy, Jarrod John, Slobedman, Barry, Abendroth, Allison
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6564036/
https://ncbi.nlm.nih.gov/pubmed/31194857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007784
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