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RNAi in Dictyostelium: The Role of RNA-directed RNA Polymerases and Double-stranded RNase
We show that in Dictyostelium discoideum an endogenous gene as well as a transgene can be silenced by introduction of a gene construct that is transcribed into a hairpin RNA. Gene silencing was accompanied by the appearance of sequence-specific RNA ∼23mers and seemed to have a limited capacity. The...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Cell Biology
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC65640/ https://ncbi.nlm.nih.gov/pubmed/11854403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.01-04-0211 |
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