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Targeting DNA-dependent protein kinase sensitizes hepatocellular carcinoma cells to proton beam irradiation through apoptosis induction

Recent studies have highlighted the implications of genetic variations in the relative biological effectiveness (RBE) of proton beam irradiation over conventional X-ray irradiation. Proton beam radiotherapy is a reasonable radiotherapy option for hepatocellular carcinoma (HCC), but the impact of gen...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Choi, Changhoon, Son, Arang, Lee, Ga-Haeng, Shin, Sung-Won, Park, Sohee, Ahn, Sang Hee, Chung, Yoonsun, Yu, Jeong Il, Park, Hee Chul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563991/
https://ncbi.nlm.nih.gov/pubmed/31194786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218049
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