Kinase network dysregulation in a human induced pluripotent stem cell model of DISC1 schizophrenia

Protein kinases orchestrate signal transduction pathways involved in central nervous system functions ranging from neurodevelopment to synaptic transmission and plasticity. Abnormalities in kinase-mediated signaling are involved in the pathophysiology of neurological disorders, including neuropsychi...

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Udgivet i:Mol Omics
Main Authors: Bentea, Eduard, Depasquale, Erica A.K., O’Donovan, Sinead M., Sullivan, Courtney R., Simmons, Micah, Meador-Woodruff, James H., Zhou, Ying, Xu, Chongchong, Bai, Bing, Peng, Junmin, Song, Hongjun, Ming, Guo-li, Meller, Jarek, Wen, Zhexing, McCullumsmith, Robert E.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563817/
https://ncbi.nlm.nih.gov/pubmed/31106784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8mo00173a
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