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Kirenol Inhibits the Function and Inflammation of Fibroblast-like Synoviocytes in Rheumatoid Arthritis in vitro and in vivo

Kirenol is a diterpenoid extracted from the Chinese herbal medicine Siegesbeckiae. Siegesbeckiae has been used to treat Rheumatoid arthritis (RA) in China for several centuries. RA is characterized by the proliferation of synoviocytes in inflamed synovia, as well as by their expression of inflammato...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Wu, Jing, Li, Qiang, Jin, Li, Qu, Yuan, Liang, Bi-Bo, Zhu, Xiao-Tong, Du, Hong-Yan, Jie, Li-Gang, Yu, Qing-Hong
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563775/
https://ncbi.nlm.nih.gov/pubmed/31244849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01304
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