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Adenine‐Driven Structural Switch from a Two‐ to Three‐Quartet DNA G‐Quadruplex
A G‐rich sequence found in the regulatory region of the RANKL gene, which is associated with homeostasis of bone metabolism, folds into a two‐quartet basket‐type G‐quadruplex stabilized by A⋅G⋅A and G⋅G⋅G base‐triads. Perusal of local structural features together with G/A‐to‐T modifications uncovere...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6563693/ https://ncbi.nlm.nih.gov/pubmed/30222243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201809328 |
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