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Molecular screening and docking analysis of LMTK3and AKT1 combined inhibitors

The abnormal activation of AKT/mTOR signaling pathway and overexpression of LMTK3, are the main factors involved in the generation of drug resistance. Therefore, the use of computer-aided drug design in the inhibitors discovery offers an advantage to provide new candidates for the treatment of this...

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Bibliografske podrobnosti
izdano v:Bioinformation
Main Authors: Allam, Loubna, Fatima, Ghrifi, Wiame, Lakhlili, Hamid, El Amri, Azeddine, Ibrahim
Format: Artigo
Jezik:Inglês
Izdano: Biomedical Informatics 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563661/
https://ncbi.nlm.nih.gov/pubmed/31223209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630014499
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