Association of MAPT Subhaplotypes With Risk of Progressive Supranuclear Palsy and Severity of Tau Pathology

IMPORTANCE: The association between the microtubule-associated protein tau (MAPT) H1 haplotype and the risk of progressive supranuclear palsy (PSP) has been well documented. However, the specific H1 subhaplotypes that drive the association have not been evaluated in large studies, nor have they been...

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Dades bibliogràfiques
Publicat a:JAMA Neurol
Autors principals: Heckman, Michael G., Brennan, Rebecca R., Labbé, Catherine, Soto, Alexandra I., Koga, Shunsuke, DeTure, Michael A., Murray, Melissa E., Petersen, Ronald C., Boeve, Bradley F., van Gerpen, Jay A., Uitti, Ryan J., Wszolek, Zbigniew K., Rademakers, Rosa, Dickson, Dennis W., Ross, Owen A.
Format: Artigo
Idioma:Inglês
Publicat: American Medical Association 2019
Matèries:
Original Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563568/
https://ncbi.nlm.nih.gov/pubmed/30882841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2019.0250
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