Poly(I:C) stimulation is superior than Imiquimod to induce the antitumoral functional profile of tumor‐conditioned macrophages

Macrophage plasticity is the ability of mononuclear phagocytes to change phenotype, function, and genetic reprogramming upon encounter of specific local stimuli. In the tumor microenvironment, Tumor‐Associated Macrophages (TAMs) acquire an immune‐suppressive and tumor‐promoting phenotype. With the a...

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Bibliographic Details
Published in:Eur J Immunol
Main Authors: Maeda, Akihiro, Digifico, Elisabeth, Andon, Fernando T., Mantovani, Alberto, Allavena, Paola
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
Subjects:
Immunomodulation and immune therapies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563448/
https://ncbi.nlm.nih.gov/pubmed/30779113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201847888
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