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Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?
All metazoans that utilize molecular oxygen (O(2)) for metabolic purposes have the capacity to adapt to hypoxia, the condition that arises when O(2) demand exceeds supply. This is mediated through activation of the hypoxia-inducible factor (HIF) pathway. At physiological oxygen levels (normoxia), HI...
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| Опубликовано в: : | Cells |
|---|---|
| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6562979/ https://ncbi.nlm.nih.gov/pubmed/31035491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8050384 |
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