Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy

Nilotinib, a tyrosine kinase inhibitor, has been studied extensively in various tumor models; however, no information exists about the pharmacological action of nilotinib in bacterial infections. Mycobacterium bovis (M. bovis) and Mycobacterium avium subspecies paratuberculosis (MAP) are the etiolog...

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Bibliographische Detailangaben
Veröffentlicht in:Cells
Hauptverfasser: Hussain, Tariq, Zhao, Deming, Shah, Syed Zahid Ali, Sabir, Naveed, Wang, Jie, Liao, Yi, Song, Yinjuan, Dong, Haodi, Hussain Mangi, Mazhar, Ni, Jiamin, Yang, Lifeng, Zhou, Xiangmei
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562972/
https://ncbi.nlm.nih.gov/pubmed/31130711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8050506
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