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YC-1 Antagonizes Wnt/β-Catenin Signaling Through the EBP1 p42 Isoform in Hepatocellular Carcinoma

Novel drugs targeting Wnt signaling are gradually being developed for hepatocellular carcinoma (HCC) treatment. In this study, we used a Wnt-responsive Super-TOPflash (STF) luciferase reporter assay to screen a new compound targeting Wnt signaling. 3-(5′-Hydroxymethyl-2′-furyl)-1-benzylindazole (YC-...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Wu, Ju-Yun, Shih, Yu-Lueng, Lin, Shih-Ping, Hsieh, Tsai-Yuan, Lin, Ya-Wen
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562864/
https://ncbi.nlm.nih.gov/pubmed/31086087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11050661
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