RAC1B Suppresses TGF-β1-Dependent Cell Migration in Pancreatic Carcinoma Cells through Inhibition of the TGF-β Type I Receptor ALK5

The small GTPase Ras-related C3 botulinum toxin substrate 1B (RAC1B) has been shown previously by RNA interference-mediated knockdown (KD) to function as a powerful inhibitor of transforming growth factor (TGF)-β1-induced cell migration and epithelial-mesenchymal transition in epithelial cells, but...

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Publicado en:Cancers (Basel)
Main Authors: Ungefroren, Hendrik, Otterbein, Hannah, Fiedler, Christian, Mihara, Koichiro, Hollenberg, Morley D., Gieseler, Frank, Lehnert, Hendrik, Witte, David
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562819/
https://ncbi.nlm.nih.gov/pubmed/31108998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11050691
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