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Inhibitory Effects of the Two Novel TSPO Ligands 2-Cl-MGV-1 and MGV-1 on LPS-induced Microglial Activation

The 18 kDa translocator protein (TSPO) ligands 2-Cl-MGV-1 and MGV-1 can attenuate cell death of astrocyte-like cells (U118MG) and induce differentiation of neuronal progenitor cells (PC-12). Lipopolysaccharide (LPS) is a bacterial membrane endotoxin that activates cellular inflammatory pathways by r...

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Publicado en:Cells
Autores principales: Monga, Sheelu, Nagler, Rafi, Amara, Rula, Weizman, Abraham, Gavish, Moshe
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562711/
https://ncbi.nlm.nih.gov/pubmed/31121852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8050486
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