Activity Improvement and Vital Amino Acid Identification on the Marine-Derived Quorum Quenching Enzyme MomL by Protein Engineering

MomL is a marine-derived quorum-quenching (QQ) lactonase which can degrade various N-acyl homoserine lactones (AHLs). Intentional modification of MomL may lead to a highly efficient QQ enzyme with broad application potential. In this study, we used a rapid and efficient method combining error-prone...

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Udgivet i:Mar Drugs
Main Authors: Wang, Jiayi, Lin, Jing, Zhang, Yunhui, Zhang, Jingjing, Feng, Tao, Li, Hui, Wang, Xianghong, Sun, Qingyang, Zhang, Xiaohua, Wang, Yan
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562636/
https://ncbi.nlm.nih.gov/pubmed/31117226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17050300
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