ZAP-70 Regulates Autoimmune Arthritis via Alterations in T Cell Activation and Apoptosis

T cells play an essential role in the pathogenesis of both human rheumatoid arthritis (RA) and its murine models. A key molecule in T cell activation is ZAP-70, therefore we aimed to investigate the effects of partial ZAP-70 deficiency on the pathogenesis of recombinant human G1(rhG1)-induced arthri...

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Bibliographic Details
Published in:Cells
Main Authors: Kugyelka, Réka, Prenek, Lilla, Olasz, Katalin, Kohl, Zoltán, Botz, Bálint, Glant, Tibor T., Berki, Timea, Boldizsár, Ferenc
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562615/
https://ncbi.nlm.nih.gov/pubmed/31137740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8050504
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