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Correction of T cell deficiency in ZAP‐70 knock‐out mice by simple intraperitoneal adoptive transfer of thymocytes
The tyrosine kinase zeta chain‐associated protein of 70 kDa (ZAP‐70) plays a key role in T cell development and signalling. In the absence of ZAP‐70, T cell development is arrested in the CD4(+)CD8(+) double‐positive stage, thus ZAP‐70 homozygous knockout (ZAP‐70(–/–)) mice have no mature T cells in...
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| Publicado no: | Clin Exp Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5980624/ https://ncbi.nlm.nih.gov/pubmed/29431868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13114 |
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