A Comparison of DNA Mutation and Copy Number Profiles of Primary Breast Cancers and Paired Brain Metastases for Identifying Clinically Relevant Genetic Alterations in Brain Metastases

Improving the systemic treatment of brain metastases (BM) in primary breast cancer (PBC) is impaired by the lack of genomic characterization of BM. To estimate the concordance of DNA copy-number-alterations (CNAs), mutations, and actionable genetic alterations (AGAs) between paired samples, we perfo...

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Detaylı Bibliyografya
Yayımlandı:Cancers (Basel)
Asıl Yazarlar: Tyran, Marguerite, Carbuccia, Nadine, Garnier, Séverine, Guille, Arnaud, Adelaïde, José, Finetti, Pascal, Touzlian, Julien, Viens, Patrice, Tallet, Agnès, Goncalves, Anthony, Metellus, Philippe, Birnbaum, Daniel, Chaffanet, Max, Bertucci, François
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562582/
https://ncbi.nlm.nih.gov/pubmed/31086113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11050665
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