Targeting Adenosine in Cancer Immunotherapy to Enhance T-Cell Function

T cells play a critical role in cancer control, but a range of potent immunosuppressive mechanisms can be upregulated in the tumor microenvironment (TME) to abrogate their activity. While various immunotherapies (IMTs) aiming at re-invigorating the T-cell-mediated anti-tumor response, such as immune...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Vigano, Selena, Alatzoglou, Dimitrios, Irving, Melita, Ménétrier-Caux, Christine, Caux, Christophe, Romero, Pedro, Coukos, George
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562565/
https://ncbi.nlm.nih.gov/pubmed/31244820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00925
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