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TAT-Modified ω-Conotoxin MVIIA for Crossing the Blood-Brain Barrier

As the first in a new class of non-opioid drugs, ω-Conotoxin MVIIA was approved for the management of severe chronic pains in patients who are unresponsive to opioid therapy. Unfortunately, clinical application of MVIIA is severely limited due to its poor ability to penetrate the blood-brain barrier...

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Bibliografske podrobnosti
izdano v:Mar Drugs
Main Authors: Yu, Shuo, Li, Yumeng, Chen, Jinqin, Zhang, Yue, Tao, Xinling, Dai, Qiuyun, Wang, Yutian, Li, Shupeng, Dong, Mingxin
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562543/
https://ncbi.nlm.nih.gov/pubmed/31083641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17050286
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