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TAT-Modified ω-Conotoxin MVIIA for Crossing the Blood-Brain Barrier

As the first in a new class of non-opioid drugs, ω-Conotoxin MVIIA was approved for the management of severe chronic pains in patients who are unresponsive to opioid therapy. Unfortunately, clinical application of MVIIA is severely limited due to its poor ability to penetrate the blood-brain barrier...

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Publicado en:Mar Drugs
Main Authors: Yu, Shuo, Li, Yumeng, Chen, Jinqin, Zhang, Yue, Tao, Xinling, Dai, Qiuyun, Wang, Yutian, Li, Shupeng, Dong, Mingxin
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562543/
https://ncbi.nlm.nih.gov/pubmed/31083641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17050286
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