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TAT-Modified ω-Conotoxin MVIIA for Crossing the Blood-Brain Barrier

As the first in a new class of non-opioid drugs, ω-Conotoxin MVIIA was approved for the management of severe chronic pains in patients who are unresponsive to opioid therapy. Unfortunately, clinical application of MVIIA is severely limited due to its poor ability to penetrate the blood-brain barrier...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Yu, Shuo, Li, Yumeng, Chen, Jinqin, Zhang, Yue, Tao, Xinling, Dai, Qiuyun, Wang, Yutian, Li, Shupeng, Dong, Mingxin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562543/
https://ncbi.nlm.nih.gov/pubmed/31083641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17050286
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