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3D-Organotypic Cultures to Unravel Molecular and Cellular Abnormalities in Atopic Dermatitis and Ichthyosis Vulgaris

Atopic dermatitis (AD) is characterized by dry and itchy skin evolving into disseminated skin lesions. AD is believed to result from a primary acquired or a genetically-induced epidermal barrier defect leading to immune hyper-responsiveness. Filaggrin (FLG) is a protein found in the cornified envelo...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Leman, Géraldine, Moosbrugger-Martinz, Verena, Blunder, Stefan, Pavel, Petra, Dubrac, Sandrine
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562513/
https://ncbi.nlm.nih.gov/pubmed/31121896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8050489
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