Impact of Extrinsic and Intrinsic Hypoxia on Catecholamine Biosynthesis in Absence or Presence of Hif2α in Pheochromocytoma Cells

Pheochromocytomas and paragangliomas (PPGLs) with activated pseudohypoxic pathways are associated with an immature catecholamine phenotype and carry a higher risk for metastasis. For improved understanding of the underlying mechanisms we investigated the impact of hypoxia and pseudohypoxia on catech...

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Publicat a:Cancers (Basel)
Autors principals: Bechmann, Nicole, Poser, Isabel, Seifert, Verena, Greunke, Christian, Ullrich, Martin, Qin, Nan, Walch, Axel, Peitzsch, Mirko, Robledo, Mercedes, Pacak, Karel, Pietzsch, Jens, Richter, Susan, Eisenhofer, Graeme
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562431/
https://ncbi.nlm.nih.gov/pubmed/31035382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11050594
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