An In Vitro System for Evaluating Molecular Targeted Drugs Using Lung Patient-Derived Tumor Organoids

Patient-derived tumor organoids (PDOs) represent a promising preclinical cancer model that better replicates disease, compared with traditional cell culture models. We have established PDOs from various human tumors to accurately and efficiently recapitulate the tissue architecture and function. Mol...

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Vydáno v:Cells
Hlavní autoři: Takahashi, Nobuhiko, Hoshi, Hirotaka, Higa, Arisa, Hiyama, Gen, Tamura, Hirosumi, Ogawa, Mayu, Takagi, Kosuke, Goda, Kazuhito, Okabe, Naoyuki, Muto, Satoshi, Suzuki, Hiroyuki, Shimomura, Kenju, Watanabe, Shinya, Takagi, Motoki
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562414/
https://ncbi.nlm.nih.gov/pubmed/31137590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8050481
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