Evaluation of anticancer agents using patient-derived tumor organoids characteristically similar to source tissues

Patient-derived tumor xenograft models represent a promising preclinical cancer model that better replicates disease, compared with traditional cell culture; however, their use is low-throughput and costly. To overcome this limitation, patient-derived tumor organoids (PDOs) were established from hum...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: Tamura, Hirosumi, Higa, Arisa, Hoshi, Hirotaka, Hiyama, Gen, Takahashi, Nobuhiko, Ryufuku, Masae, Morisawa, Gaku, Yanagisawa, Yuka, Ito, Emi, Imai, Jun-Ichi, Dobashi, Yuu, Katahira, Kiyoaki, Soeda, Shu, Watanabe, Takafumi, Fujimori, Keiya, Watanabe, Shinya, Takagi, Motoki
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072291/
https://ncbi.nlm.nih.gov/pubmed/29917168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2018.6501
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