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The Alzheimer's Prevention Initiative Generation Program: Study design of two randomized controlled trials for individuals at risk for clinical onset of Alzheimer's disease

INTRODUCTION: Alzheimer's disease (AD) pathology, including the accumulation of amyloid beta (Aβ) species and tau pathology, begins decades before the onset of cognitive impairment. This long preclinical period provides an opportunity for clinical trials designed to prevent or delay the onset o...

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Библиографические подробности
Опубликовано в: :Alzheimers Dement (N Y)
Главные авторы: Lopez Lopez, Cristina, Tariot, Pierre N., Caputo, Angelika, Langbaum, Jessica B., Liu, Fonda, Riviere, Marie-Emmanuelle, Langlois, Carolyn, Rouzade-Dominguez, Marie-Laure, Zalesak, Martin, Hendrix, Suzanne, Thomas, Ronald G., Viglietta, Vissia, Lenz, Rob, Ryan, J. Michael, Graf, Ana, Reiman, Eric M.
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562315/
https://ncbi.nlm.nih.gov/pubmed/31211217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trci.2019.02.005
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