The Alzheimer's Prevention Initiative Generation Program: Study design of two randomized controlled trials for individuals at risk for clinical onset of Alzheimer's disease

INTRODUCTION: Alzheimer's disease (AD) pathology, including the accumulation of amyloid beta (Aβ) species and tau pathology, begins decades before the onset of cognitive impairment. This long preclinical period provides an opportunity for clinical trials designed to prevent or delay the onset o...

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Vydáno v:Alzheimers Dement (N Y)
Hlavní autoři: Lopez Lopez, Cristina, Tariot, Pierre N., Caputo, Angelika, Langbaum, Jessica B., Liu, Fonda, Riviere, Marie-Emmanuelle, Langlois, Carolyn, Rouzade-Dominguez, Marie-Laure, Zalesak, Martin, Hendrix, Suzanne, Thomas, Ronald G., Viglietta, Vissia, Lenz, Rob, Ryan, J. Michael, Graf, Ana, Reiman, Eric M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Perspective
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562315/
https://ncbi.nlm.nih.gov/pubmed/31211217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trci.2019.02.005
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