Non-coding cis-element of Period2 is essential for maintaining organismal circadian behaviour and body temperature rhythmicity

Non-coding cis-regulatory elements are essential determinants of development, but their exact impacts on behavior and physiology in adults remain elusive. Cis-element-based transcriptional regulation is believed to be crucial for generating circadian rhythms in behavior and physiology. However, gene...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Doi, Masao, Shimatani, Hiroyuki, Atobe, Yuta, Murai, Iori, Hayashi, Hida, Takahashi, Yukari, Fustin, Jean-Michel, Yamaguchi, Yoshiaki, Kiyonari, Hiroshi, Koike, Nobuya, Yagita, Kazuhiro, Lee, Choogon, Abe, Manabu, Sakimura, Kenji, Okamura, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561950/
https://ncbi.nlm.nih.gov/pubmed/31189882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10532-2
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