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The domain swapping of human cystatin C induced by synchrotron radiation

Domain swapping is observed for many proteins with flexible conformations. This phenomenon is often associated with the development of conformational diseases. Importantly, domain swapping has been observed for human cystatin C (HCC), a protein capable of forming amyloid deposits in brain arteries....

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Taube, Michal, Pietralik, Zuzanna, Szymanska, Aneta, Szutkowski, Kosma, Clemens, Daniel, Grubb, Anders, Kozak, Maciej
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561922/
https://ncbi.nlm.nih.gov/pubmed/31189973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44811-1
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