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The domain swapping of human cystatin C induced by synchrotron radiation

Domain swapping is observed for many proteins with flexible conformations. This phenomenon is often associated with the development of conformational diseases. Importantly, domain swapping has been observed for human cystatin C (HCC), a protein capable of forming amyloid deposits in brain arteries....

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Publicado en:Sci Rep
Main Authors: Taube, Michal, Pietralik, Zuzanna, Szymanska, Aneta, Szutkowski, Kosma, Clemens, Daniel, Grubb, Anders, Kozak, Maciej
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561922/
https://ncbi.nlm.nih.gov/pubmed/31189973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44811-1
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