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Dexamethasone induces primary amnion epithelial cell senescence through telomere-P21 associated pathway()

Dexamethasone (Dex), a corticosteroid hormone, is used during the perinatal period to help fetal lung and other organ development. Conversely, Dex-induced cell proliferation has been associated with accelerated aging. Using primary amnion epithelial cells (AECs) from term, not in labor, fetal membra...

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Bibliografische gegevens
Gepubliceerd in:Biol Reprod
Hoofdauteurs: Martin, Laura F, Richardson, Lauren S, da Silva, Márcia Guimarães, Sheller-Miller, Samantha, Menon, Ramkumar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561861/
https://ncbi.nlm.nih.gov/pubmed/30927408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioz048
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