Protein Kinase C Alpha is Upregulated by IMP1 in Melanoma and is Linked to Poor Survival

The oncofetal mRNA binding protein, IMP1 or insulin-like growth factor-2 mRNA-binding protein 1 [IGF2BP1], promotes the overexpression of several oncogenic proteins by binding to and stabilizing their mRNAs. IMP1 is frequently overexpressed in melanoma and is associated with a poor prognosis, but th...

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Detalhes bibliográficos
Publicado no:Melanoma Res
Main Authors: Mahapatra, Lily, Andruska, Neal, Mao, Chengjian, Gruber, Stephen B., Johnson, Timothy M., Fullen, Douglass R., Raskin, Leon, Shapiro, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561837/
https://ncbi.nlm.nih.gov/pubmed/30543563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0000000000000558
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