A carregar...
Estrogen receptor α inhibitor activates the unfolded protein response, blocks protein synthesis, and induces tumor regression
Recurrent estrogen receptor α (ERα)-positive breast and ovarian cancers are often therapy resistant. Using screening and functional validation, we identified BHPI, a potent noncompetitive small molecule ERα biomodulator that selectively blocks proliferation of drug-resistant ERα-positive breast and...
Na minha lista:
| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4403155/ https://ncbi.nlm.nih.gov/pubmed/25825714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403685112 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|