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Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint

Coordination of the cellular response to DNA damage is organised by multi-domain ‘scaffold’ proteins, including 53BP1 and TOPBP1, which recognise post-translational modifications such as phosphorylation, methylation and ubiquitylation on other proteins, and are themselves carriers of such regulatory...

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Podrobná bibliografie
Vydáno v:eLife
Hlavní autoři: Bigot, Nicolas, Day, Matthew, Baldock, Robert A, Watts, Felicity Z, Oliver, Antony W, Pearl, Laurence H
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561707/
https://ncbi.nlm.nih.gov/pubmed/31135337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44353
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