Class I histone deacetylase inhibitor suppresses vasculogenic mimicry by enhancing the expression of tumor suppressor and anti-angiogenesis genes in aggressive human TNBC cells

Triple-negative breast cancer (TNBC) cells form angiogenesis-independent vessel-like structures to survive, known as vasculogenic mimicry (VM), contributing to a poor prognosis for cancer patients. Nuclear localized class I histone deacetylases (HDACs) enzymes, particularly HDACs 1, 2, 3 deacetylate...

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Bibliografiske detaljer
Udgivet i:Int J Oncol
Main Authors: Maiti, Aparna, Qi, Qianya, Peng, Xuan, Yan, Li, Takabe, Kazuaki, Hait, Nitai C.
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2019
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561627/
https://ncbi.nlm.nih.gov/pubmed/31059004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2019.4796
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