Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses vasculogenic mimicry and proliferation of highly aggressive pancreatic cancer PaTu8988 cells

BACKGROUND: Pancreatic cancer is one of the most aggressive human malignancies with a extremely low 5-year survival rate. Hence, the search for more effective anti-pancreatic cancer agents is urgent. METHODS: PaTu8988 pancreatic cancer cells were treated with different concentrations of suberoylanil...

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Main Authors: Xu, Xing-dong, Yang, Lan, Zheng, Li-yun, Pan, Yan-yan, Cao, Zhi-fei, Zhang, Zhi-qing, Zhou, Quan-sheng, Yang, Bo, Cao, Cong
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047270/
https://ncbi.nlm.nih.gov/pubmed/24886166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-373
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