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Mitotane induces mitochondrial membrane depolarization and apoptosis in thyroid cancer cells
Mitotane is used for the treatment of adrenocortical cancer and elicits its anticancer effects via inhibition of mitochondrial respiration. Targeting mitochondria-dependent metabolism has emerged as a promising strategy for thyroid cancer (TC) treatment. We hypothesized that mitotane targets mitocho...
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| Publicado en: | Int J Oncol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
D.A. Spandidos
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6561621/ https://ncbi.nlm.nih.gov/pubmed/31115496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2019.4802 |
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