Mitotane induces mitochondrial membrane depolarization and apoptosis in thyroid cancer cells

Mitotane is used for the treatment of adrenocortical cancer and elicits its anticancer effects via inhibition of mitochondrial respiration. Targeting mitochondria-dependent metabolism has emerged as a promising strategy for thyroid cancer (TC) treatment. We hypothesized that mitotane targets mitocho...

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Detaylı Bibliyografya
Yayımlandı:Int J Oncol
Asıl Yazarlar: Bikas, Athanasios, Jensen, Kirk, Patel, Aneeta, Costello, John, Kaltsas, Gregory, Hoperia, Victoria, Wartofsky, Leonard, Burman, Kenneth, Vasko, Vasyl
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: D.A. Spandidos 2019
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561621/
https://ncbi.nlm.nih.gov/pubmed/31115496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2019.4802
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