Mitotane induces mitochondrial membrane depolarization and apoptosis in thyroid cancer cells

Mitotane is used for the treatment of adrenocortical cancer and elicits its anticancer effects via inhibition of mitochondrial respiration. Targeting mitochondria-dependent metabolism has emerged as a promising strategy for thyroid cancer (TC) treatment. We hypothesized that mitotane targets mitocho...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Oncol
Prif Awduron: Bikas, Athanasios, Jensen, Kirk, Patel, Aneeta, Costello, John, Kaltsas, Gregory, Hoperia, Victoria, Wartofsky, Leonard, Burman, Kenneth, Vasko, Vasyl
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: D.A. Spandidos 2019
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561621/
https://ncbi.nlm.nih.gov/pubmed/31115496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2019.4802
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